At SyntheX, we have built synthetic biology based selection platforms, ToRPPIDO and ToRNeDO, to produce and functionally select molecules to target conventionally 'undruggable' proteins. Our first in class platforms focus on disrupting protein-protein interactions and discovering novel protein degraders.
Our platforms enable the discovery of compounds that can explore novel biology. Using unbiased selection, we can uncover novel allosteric pockets and mechanisms.
Using our cell-based platforms, we can engineer complex selection readouts to efficiently identify candidate molecules from a first pass functional selection.